Monday, September 14, 2009

statins -- keywords

The first search statement shown below was produced by ORing together the synonyms from the MICROMEDEX POISINDEX Managements article "LOVASTATIN AND RELATED DRUGS" and the American trade names from AHFS Drug Information. (CAS numbers from the MICROMEDEX article were not included.) Alternate forms of investigational names were inserted.

("HMG-CoA Reductase Inhibitors" OR "HMG-CoA Reductase Inhibitor" OR statin OR statins OR LOVASTATIN OR "L-154803" OR "L154803" OR "L 154803" OR "MB-530B" OR "MB530B" OR "MB 530B" OR "6-alpha methylcompactin" OR Mevinacor OR Mevinic OR Mevinolin OR Mevlor OR "MK-803" OR "MK803" OR "MK 803" OR Monacolin OR "MSD-803" OR "MSD803" OR "MSD 803"OR mevacor OR altoprev OR CERIVASTATIN OR "BAY W6228" OR "BAY-W6228" OR "BAYW6228" OR FLUVASTATIN OR "XU-62-320" OR "XU62-320" OR "XU 62-320" OR lescol OR ATORVASTATIN OR lipitor OR caduet OR "CI-981" OR "CI981" OR "CI 981" OR PITAVASTATIN OR Itavastatin OR Nisvastatin OR "NK-104" OR "NK104" OR "NK 104" OR "NKS-104" OR "NKS104" OR "NKS 104" OR "P-872441" OR "P872441" OR "P 872441" OR PRAVASTATIN OR "CS-514" OR "CS514" OR "CS 514" OR Eptastatin OR "3-beta-Hydroxycompactin" OR Pravachol OR ROSUVASTATIN OR Crestor OR "ZD4522" OR "ZD 4522" OR "ZD-4522" OR SIMVASTATIN OR "L-644128-OOOU" OR "L644128OOOU" OR "L 644128-OOOU" OR "MK-733" OR "MK733" OR "MK 733" OR Synvinolin OR zocor )

The search statement (see above) was then test-run in PubMed. After the test run, it was clear that phrases and terms not recognized by PubMed would have to be removed as too many irrelevant results were being retrieved. I've removed the unrecognized phrases and terms from the search statement below:

("HMG-CoA Reductase Inhibitors" OR "HMG-CoA Reductase Inhibitor" OR statin OR statins OR LOVASTATIN OR "MB-530B" OR "MB 530B" OR Mevinacor OR Mevinic OR Mevinolin OR Mevlor OR "MK-803" OR "MK803" OR "MK 803" OR Monacolin OR mevacor OR altoprev OR CERIVASTATIN OR "BAYW6228" OR FLUVASTATIN OR "XU-62-320" OR "XU62-320" OR "XU 62-320" OR lescol OR ATORVASTATIN OR lipitor OR caduet OR "CI-981" OR "CI 981" OR PITAVASTATIN OR Itavastatin OR Nisvastatin OR "NK-104" OR "NK104" OR "NK 104" OR "P-872441" OR "P 872441" OR PRAVASTATIN OR "CS-514" OR "CS514" OR "CS 514" OR Eptastatin OR "3-beta-Hydroxycompactin" OR Pravachol OR ROSUVASTATIN OR Crestor OR "ZD4522" OR SIMVASTATIN OR "MK-733" OR "MK733" OR "MK 733" OR Synvinolin OR zocor )